4 Temmuz 2012 Çarşamba

Causes and Symptoms of Cirrhosis and its Treatments

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Causes and Symptoms of Cirrhosis

Alcoholism is the primary cause of cirrhosis, owing to a combination of the alcoholic’s poor diet and the direct effects of alcohol. Many alcoholics are also infected with hepatitis C. chronic viral hepatitis (types B, C, and D) or chronic autoimmune hepatitis may lead to cirrhosis. Some hereditary diseases, such as cystic fibrosis, hemochromatosis (iron accumulation), and Wilson’s disease (deposition of copper), may injure the liver. Bile ducts, through which bile is released to the intestines to aid in digestion, may become blocked, inflamed, or scarred, resulting in a type of cirrhosis called biliary cirrhosis. The common bile duct may also be injured during gallbladder surgery. Prolonged exposure to certain medications, or to toxic chemicals like insecticides, herbicides, and cleaning solvents may harm the liver. Congestive heart failure may lead to cirrhosis. Nonalcoholic steatohepatitis, which sometimes accompanies obesity, diabetes or lipid disorders, may result in cirrhosis.

Symptoms
No symptoms in early stages. Loss of appetite, weight loss, nausea, and diarrhea. Fatigue, weakness and exhaustion. Jaundice, small, red, spidery veins (spider nevi) appearing on the skin, along with a tendency to bruise or bleed easily; severe itching. Swelling in the legs and ankles (edema) or abdomen (ascites) and darkened urine. Impotence, testicular atrophy, and enlarged breast in men; cessation of menstruation in women. Black or bloody stools, vomiting of blood. Inability to concentrate impaired memory and irritability as well as mental confusion and trembling hands.

Diagnosis
• In late stages of cirrhosis, diagnosis is very often evident from the history and findings on physical examination. Other tests mentioned are confirmatory in late stages but essential in early stages.
• Blood tests are conducted to measure the synthesis of certain proteins by the liver and any increased release of certain enzymes that indicate inflammation. Blood tests are also done to detect the presence of hepatitis B or C.
• A liver biopsy or scan may be done.
• In some cases, the liver may be examined with a viewing instrument (laparoscope) inserted through a small incision in the abdomen.

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PREVENTION AND TREATMENT FOR CIRROHOSIS
Cirrhosis is characterized by progressive destruction of liver cells and the formation of fibrous scar tissue. The loss of liver cells interferes with the organ’s ability to process nutrients, hormones, and drugs and slows the production of protein other important substances manufactured in the liver. Eventually liver failure may result. The scar tissue interferes with blood flow from the entire gastrointestinal tract through the liver via the portal vein. Pressure in the portal vein increases (portal hypertension), the spleen becomes enlarged, and blood is shunted around the liver through enlarged, fragile veins (varices) in the stomach and esophagus. Toxic substances formed in the intestine, and normally cleared in the liver, bypass the liver and are carried to the brain, where they can interfere with its function (hepatic encephalopathy). People with cirrhosis may exhibit no symptoms until the damage – which is irreversible is quite extensive. Cirrhosis is more common among men than women, and some forms of it are associated with and increased risk of liver cancer.

Prevention
Consume no more than two drinks a day. If you suspect that you may have a drinking problem, seek help immediately. You will need to avoid alcohol completely in order to halt the progress of cirrhosis, and a doctor or support group can help you achieve this goal. Eat a healthy, balanced diet.

Treatment
Combination of conventional and alternative therapy is one of the surest ways in prevention and treatment for cirrhosis.
• Stop drinking alcohol completely. Even if cirrhosis is not alcohol induced, the liver may be further damaged by alcohol.
• Avoid any toxins or medications that cause liver injury.
• If swelling in the legs, ankles, or abdomen is present, eat a low salt diet to reduce fluid retention. (Diuretics may be prescribed for this purpose as well.)
• Antibiotics may be prescribed if excess fluid retained in the abdomen has become infected.
• Cholestyramine may be prescribed to relieve severe itching by binding bile salts in the small intestine.
• Antihypertensive drugs such beta-blockers may be prescribed to lower pressure within the portal vein and thus reduce the risk of bleeding from esophageal varices.
• Endoscopic procedures to close off esophageal varices may be warranted.
• Restriction of dietary protein may ease or prevent neurological changes (hepatic encephallopathy).
• Laxatives (such as lactulose) may be used to speed the passage of toxins through the intestine.
• In advance cases of cirrhosis, a liver transplant may be recommended
• Herbs such as alfalfa helps to build a healthy digestive tract and is a good source of vitamin k. it helps to prevent bleeding as a result of vitamin k deficiency, which is common with cirrhosis. It can be taken in tablet or liquid form.
• Aloe Vera helps to cleanse and heal the digestive tract. Drink ¼ cup of aloe Vera juice every morning and evening. George aloe Vera juice from warren laboratories is a good product.
• Burdock root, dandelion, and red clover aid in liver repair by cleansing the blood stream.
• Silymarin (milk thistle extract) has been shown in scientific studies to repair and rejuvenate the liver. Take 200 milligrams of silymarin three times daily. Liv-R-Actin from natures plus is also a good source of milk thistle.
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